Cell Biology - Kyorin University Medical School
Cell Biology in English, Spring Term 2018

         

Textbook:
MOLECULAR BIOLOGY OF THE CELL, Alberts et al., 2014, 6th Edition

Bovine Pulmonary Artery Endothelial Cells (BPAE Line)

BPAE cells are positive for angiotensin converting enzyme (ACE), an enzyme that is intricately involved in the maintenance of blood pressure and volume. Due to this fact, BPAE cells are often utilized in hypertension research as well as studies of atherosclerosis and coronary heart disease.

UPDATES !


LECTURE UPDATE

June 29th class will be :
Intracellular and whole cell movement

July 6th class will be :
Skeletal muscle

June 13th class will be :
Cell division


ADDITIONS UPDATE

Medical Topics Guide (.pdf) added to Reading Material list
Genetic code (.jpg) added to Reading Material list

Reading Material from the textbook is available. Click on the topic to download the .pdf

Chapter 1. Cells and genomes
Chapter 4. DNA, chromosomes, and genomes
Chapter 6. How cells read the genome: from DNA to protein
Chapter 10. Membranes
Chapter 12. Intracellular compartments and protein sorting
Chapter 13. Intracellular membrane traffic
Chapter 14. Energy conversion: mitochondria
Chapter 16. Cytoskeleton
Chapter 17. Cell cycle

Medical Topics Guide

Genetic Code

Lecture slides. Click on the topic to view the slides ...
 
MEMBRANES

NUCLEUS

TRANSCRIPTION/TRANSLATION PART 1

TRANSCRIPTION/TRANSLATION PART 2

TRANSCRIPTION/TRANSLATION PART 3

ENDOMEMBRANE SYSTEM PART 1 The role of the ER

ENDOMEMBRANE SYSTEM PART 2 Vesicles, GA, Lysosome

ENERGY : Mitochondria and chloroplasts

CYTOSKELETON : Introduction

CYTOSKELETON : Intracellular and whole cell movement

CYTOSKELETON : Actin, myosin, and muscle

CYTOSKELETON : The cell cycle

Assignments

Assignment 1. Draw diagrams showing the compartmentation of an animal cell in 2-dimensions. On the front page show a general view of the cell; on the reverse side draw the main organelles in detail. Label everything that you draw, but in particular label the membranes (eg plasma membrane). Don’t draw too small !

Assignment 1.5. Draw diagrams to show details of the basic structure of membranes and how proteins might be embedded into the membrane. Label everything that you draw.

Assignment 2. Draw diagrams to show details of the nuclear pore, and to explain how molecules enter and exit the nucleus. Label everything that you draw.

Assignment 3. Draw basic diagrams to show details of DNA and RNA, and how RNA is synthesised (transcription). Label everything that you draw.

Assignment 4. Draw basic diagrams to show how mRNA is translated into proteins. Use both sides of the paper to show explanatory diagrams of the process. Label everything that you draw.

Assignment 5. Draw basic diagrams to show co-translational protein insertion into the ER and glycosylation. Use both sides of the paper to show explanatory diagrams of the process. Label everything that you draw.

Assignment 6. Draw basic diagrams to show how molecules are transported to the GA by vesicles and how they are modified in the GA. Also explain how the CGN is proposed to form, and the general dynamics of the GA. Use both sides of the paper to show explanatory diagrams of the process. Label everything that you draw. 頑張って!

Assignement 7. Draw basic diagrams to show how energy is made in both mitochondria and chloroplasts. Use both sides of the paper to show explanatory diagrams of the process. Label everything that you draw. 頑張って!

Assignment 8. Draw basic diagrams to show basic information for the three main elements of the cytoskeleton. Use both sides of the paper to show explanatory diagrams of MT and MF dynamics. Label everything that you draw.

Assignment 9. Draw basic diagrams to explain intracellular movement and how whole cells move. Include details on how motor proteins provide the basis for movement. Use both sides of the paper. Label everything that you draw.

Assignment 10. Draw basic diagrams to explain how muscle works. Use both sides of the paper. Label everything that you draw.

Assignment 11. (Extra paper) Draw basic diagrams to explain mitosis and meiosis. Include information related to cyclins and control points throughout the cell cycle. Label everything.